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The review was supported by Charles University, Faculty of Medicine in Hradec Kralove, the Czech Republic, by project SVV-2025-260776

Ferroptosis inhibition by lysosome-dependent catabolism of extracellular protein

CRC is a multifactorial disease, with modifiable risk factors such as high intake of processed or red meat, low consumption of dietary fiber, fruits, and vegetables, along with smoking, excessive alcohol use, and lack of physical activity [215]